Dr Edward Bertram

Dr Edward Bertram is Head of Scientific Programs at the Australian Phenomics Facility and Group Leader, Anti-Viral T cell costimulation and Memory Group in the Immunogenomics Laboratory at The John Curtin School of Medical Research. He completed his PhD at the University of Adelaide in 1997 and developed a research career at the University of Toronto studying the role of costimulatory cell surface molecules on CD8 T cells in the context of anti-viral immunity. During this time he was a member of CANVAC- Canadian Network for Vaccines and immunotherapeutics. His current research interests include regulation of CD8+ T cell immune responses using influenza virus as a model pathogen and the role that costimulatory molecules such as LIGHT:HVEM and 4-1BBL:4-1BB, as well signals transduced from costimulatory molecules via Carma-1 influence the differentiation of CD8 + T cells. He is also using a unique collection of mouse pedigrees at the Australian Phenomics Facility, bearing chemically induced single base DNA changes across the genome have been undergoing a systematic screen to identify pedigrees with novel genes that regulate the development of CD8 T cell memory and recall responses to influenza virus.